*Geek Box: Vitamin D Metabolism
*Geek Box: Vitamin D Metabolism The production of vitamin D starts in the skin with exposure to UVB radiation from sunlight. A sterol compound in...
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*Geek Box: Phenome-Wide Association Studies
*Geek Box: Phenome-Wide Association Studies As a result of mapping the human genome, the technology is now available for research to analyse over a million...
*Geek Box: Glycaemic Measures of AUC and the MAGE
*Geek Box: Glycaemic Measures of AUC and the MAGE The “area under the curve” [AUC] is a mathematical calculation that provides a measure of the...
*Geek Box: Glycaemic Index & Glycaemic Load
*Geek Box: Glycaemic Index & Glycaemic Load The glycaemic index [GI] of a food is based on comparing how quickly a food makes blood glucose...
*Geek Box: Nested-Case Control Study
*Geek Box: Nested-Case Control Study A nested case-control design is termed “nested” because the study participants are sampled from within a larger cohort. In a...
*Geek Box: Bioelectrical Impedance Analysis and the Phase Angle
*Geek Box: Melatonin, “Circadian Time” and “Clock Time” Bioelectrical impedance analysis [BIA] is a method of assessing body composition and additional parameters, such as body...
*Geek Box: Melatonin, “Circadian Time” and “Clock Time”
*Geek Box: Melatonin, “Circadian Time” and “Clock Time” Melatonin is produced and secreted from the pineal gland, but the rhythm in melatonin is generated by...
*Geek Box: Scoping Review vs. Systematic Review
*Geek Box: Scoping Review vs. Systematic Review Most of you will be familiar with systematic reviews, which apply specific inclusion criteria and aim to provide...
*Geek Box: Atherogenicity of LDL Particles
*Geek Box: Atherogenicity of LDL Particles LDL particles pass through the arterial endothelium and enter the arterial intima, where the apolipoprotein B [ApoB] protein binds...
*Geek Box: Two-Sample Mendelian Randomisation
*Geek Box: Two-Sample Mendelian Randomisation Mendelian Randomisation (MR) reflects the fact that the genes you inherit from your parents were “assigned” to you randomly. MR...
*Geek Box: Plasma Glucose vs. CGMs
*Geek Box: Plasma Glucose vs. CGMs The standard reference method for measuring glucose levels in the body, either fasted or in response to food, is...
*Geek Box: Methods of Measuring Energy Expenditure in Humans
*Geek Box: Methods of Measuring Energy Expenditure in Humans If you read metabolic ward studies, you may come across the term “respiratory chamber” and see...