*Geek Box: Reviews
*Geek Box: Reviews Reviews are common in research, and have the potential to be valuable to both peers in a given field as well as practitioners, by...
Blog: Archive
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*Geek Box: P-values vs. Confidence Intervals
*Geek Box: P-values vs. Confidence Intervals Most of us are not statisticians, and yet statistics are at the core of science. This means that often,...
*Geek Box: Determining Chronotype
*Geek Box: Determining Chronotype The concept of a “chronotype” denotes, a phenotype reflecting an individuals’ time of day preferences. This has historically been considered a psychological construct,...
*Geek Box: Different Clocks of Life
*Geek Box: Biological, Social, and Solar Clocks Reading any circadian or chrononutrition research can mean seeing continued reference to “clocks”, and it can become confusing as...
*Geek Box: Retrospective Analysis
*Geek Box: Retrospective Analysis If you’ve heard of a retrospective study, most likely it is in the context of a retrospective cohort study, in which the...
*Geek Box: The ‘ATE’
*Geek Box: Average Treatment Effect One of the main reasons why RCTs are considered more reliable than other research designs is that the size of the...
*Geek Box: Mendelian Randomisation
*Geek Box: Mendelian Randomisation Mendelian randomisation [MR] is a principle of using genetics to mimic a long-term randomised controlled trial [see figure, below], particularly where...
*Geek Box: Classifying Biomarkers
*Geek Box: Causal Risk Factors vs. Systems Biomarkers Studies investigating diet and health outcomes may use any number of measures to test effects of diet....
*Geek Box: Measuring Insulin Sensitivity
*Geek Box: Hyperinsulinemic-euglycemic clamp & HOMA-IR You will inevitably come across certain investigative techniques in research papers, particularly if you have an interest any condition...
*Geek Box: Fat Cell Types
*Geek Box: Hypertrophic vs. Hyperplastic Adipocytes The ability for fat cells to store excess energy in the form of triglycerides is critical to metabolic health, and whether increasing adiposity is...
*Geek Box: Semi-Quantitative FFQ
*Geek Box: Semi-Quantitative FFQ The conceptual basis of food-frequency questionnaires [FFQ], as the primary dietary assessment method in nutritional epidemiology, is dietary intake over a...
*Geek Box: Diet Quality Indices
*Geek Box: Diet Quality Indices Most approaches to dietary assessment in nutritional epidemiology focus on individual foods and nutrients as the exposure of interest. However,...