Blog: Archive

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*Geek Box: VLDL

*Geek Box: Very-Low-Density Lipoprotein  Most people are very familiar with low-density lipoprotein - LDL, the “bad cholesterol” - but not as familiar with its very-low...
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*Geek Box: Research Methods

*Geek Box: Cluster Randomisation When you read about ‘randomisation’ in a study, more often than not this is referring to randomising of individuals - often...
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*Geek Box: Mechanisms

*Geek Box: The Methylation Cycle It’s important for the context of this study, and anything related to homocysteine, to understand the methylation cycle. A methyl...
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*Geek Box: Statistical Methods

*Geek Box: Sensitivity Analysis When reading research papers, you will inevitably come across the term ’sensitivity analysis’ in the methods section, so it is helpful...
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*Geek Box: Research Designs

*Geek Box: Meta-Analysis The term ‘meta-analysis’ first entered scientific terminology in 1976 in a paper by psychologist Gene Glass. The intended outcome of a meta-analysis...
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*Geek Box: Statistical Methods

*Geek Box: Substitution Models There are two ways to think about potential confounders in nutritional epidemiology: confounding from other non-dietary lifestyle factors, like smoking, and...
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*Geek Box: Dietary Assessment Methods

*Geek Box: Dietary Assessment in the Nurses' Health Study When it comes to dietary assessment in nutritional epidemiology, we know that validation process is integral...
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*Geek Box: Statistical Methods

*Geek Box: Linear Regression You’ll likely come across the statistical method known as ‘linear regression’ very regularly when reading research. So what is it? Linear...
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*Geek Box: The ‘Twin Cycle Hypothesis’

*Geek Box: The 'Twin Cycle Hypothesis' The earliest detectable characteristic of deteriorating glucose tolerance is insulin resistance in skeletal muscle tissue, which is followed by...
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*Geek Box: Measuring Sleep

*Geek Box: Actigraphy & Polysomnograpny Other than questionnaires for subjective sleepiness, two primary methods are used in research to assess sleep: actigraphy and polysomnography [PSG]....
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*Geek Box: Time-of-Day Preference

*Geek Box: Chronotypes All of our internal circadian rhythms are synchronised to the 24hr day, however, the exact timing of the peaks, troughs, and overall...
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*Geek Box: Pooled Analysis

*Geek Box: Pooled Analysis You’ll have come across meta-analysis over and over in reading research, but a pooled analysis is same-same-but-different. Both meta and pooled...
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