*Geek Box: Mendelian Randomisation Mendelian randomisation [MR] is a principle of using genetics to mimic a long-term randomised controlled trial …

*Geek Box: Causal Risk Factors vs. Systems Biomarkers Studies investigating diet and health outcomes may use any number of measures …

*Geek Box: Hyperinsulinemic-euglycemic clamp & HOMA-IR You will inevitably come across certain investigative techniques in research papers, particularly if you …

*Geek Box: Hypertrophic vs. Hyperplastic Adipocytes The ability for fat cells to store excess energy in the form of triglycerides …

*Geek Box: Semi-Quantitative FFQ The conceptual basis of food-frequency questionnaires [FFQ], as the primary dietary assessment method in nutritional epidemiology, …

*Geek Box: Diet Quality Indices Most approaches to dietary assessment in nutritional epidemiology focus on individual foods and nutrients as …

*Geek Box: Very-Low-Density Lipoprotein  Most people are very familiar with low-density lipoprotein – LDL, the “bad cholesterol” – but not …

*Geek Box: Cluster Randomisation When you read about ‘randomisation’ in a study, more often than not this is referring to …

*Geek Box: The Methylation Cycle It’s important for the context of this study, and anything related to homocysteine, to understand …

*Geek Box: Sensitivity Analysis When reading research papers, you will inevitably come across the term ’sensitivity analysis’ in the methods …