*Geek Box: Meta-Analysis
*Geek Box: Meta-Analysis The term “meta-analysis” was coined in 1976 by a psychologist, Gene Glass, as “an analysis of analyses”. The conceptual basis was a means to address the...
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*Geek Box: Sir Austin Bradford-Hill
*Geek Box: Bradford-Hill Criteria In 1965, Sir Austin Bradford Hill described his criteria for inferring causation, a framework that encapsulates the concept of considering converging...
*Geek Box: Cross Sectional Study
*Geek Box: Cross-Sectional Study A cross sectional study is a type of observational study design, where data is analysed from a sample population at a specific...
*Geek Box: Adjustment
*Geek Box: Statistical Adjustment Reading research, you’ll come across the term ’adjusted’ or ‘controlled’, i.e., a relationship between exposure A and outcome B was significant, but then after adjusting...
*Geek Box: Internal vs. External Validity
*Geek Box: Internal vs. External Validity ‘Internal validity’ is the term for the criteria that are considered necessary for a trial to demonstrate causation. Randomisation, strict double-blinding, placebo...
*Geek Box: Respiratory Quotient
*Geek Box: Respiratory Quotient To determine how much energy we use at rest, known as ‘resting metabolic rate’ [RMR], how much energy we are using after...
*Geek Box: Glycaemic Variability
*Geek Box: Glycaemic Variability Numerous blood glucose measures may be used in research, and if you have an interest in diabetes research, you’re going to...
*Geek Box: Parallel Design
*Geek Box: Parallel Design You’ve likely heard of randomised controlled trials referred to as the “gold standard” research design, and a parallel design is the...
*Geek Box: CAC
*Geek Box: Coronary Artery Calcification Calcification of tissues is a process that can occur in response to injury. In the process of atherosclerosis development –...
*Geek Box: Fatty Acids
*Geek Box: Understanding Fatty Acids If you read nutrition research enough, you’re going to read a lot about dietary fatty acids, some of them with...
*Geek Box: Oxidative Stress
*Geek Box: Oxidative Stress You’ve likely heard this term, and you’ve definitely heard the term ‘antioxidant’ but what do they really mean? In order to...
*Geek Box: Beta-Cells and Diabetes
*Geek Box: Beta-Cells & Diabetes Beta-cells of the pancreas release insulin in response to increases in blood glucose after a meal. Although insulin resistance, i.e.,...