« Back to Research Deepdives

High Artificial Sweeteners Intake and Type-2 Diabetes Risk

This content is restricted to members.

To view our premium content, sign up for a membership:

 

Register New Account

Choose your membership level

Choose Your Payment Method

‹ Back to Research Deepdives

References

  1. Cooper RM. Saccharin—Of Risk and Democracy. Food Drug Cosmet Law J. 1985 Jan;40(1):34–65.
  2. Southwick TP. FDA Extends Ban on Cyclamates. Science (1979). 1970 Sep 4;169(3949):962–962.
  3. Food E, Authority S. Statement of EFSA on the scientific evaluation of two studies related to the safety of artificial sweeteners. EFSA J. 2011;9(2):2089.
  4. Marinovich M, Galli CL, Bosetti C, Gallus S, La Vecchia C. Aspartame, low-calorie sweeteners and disease: Regulatory safety and epidemiological issues. Food Chem Toxicol. 2013;60:109–15.
  5. Gardner C. Non-nutritive sweeteners: Evidence for benefit vs. risk. Curr Opin Lipidol. 2014;25(1):80–4.
  6. Peters JC, Beck J. Low Calorie Sweetener (LCS) use and energy balance. Physiol Behav. 2016;164:524–8.
  7. Kim Y, Keogh JB, Clifton PM. Consumption of a Beverage Containing Aspartame and Acesulfame K for Two Weeks Does Not Adversely Influence Glucose Metabolism in Adult Males and Females: A Randomized Crossover Study. Int J Environ Res Public Health. 2020 Dec 4;17(23):9049.
  8. Suez J, Cohen Y, Valdés-Mas R, Mor U, Dori-Bachash M, Federici S, et al. Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance. Cell. 2022 Sep;185(18):3307-3328.e19.
  9. Romo-Romo A, Aguilar-Salinas CA, Brito-Cordova GX, Diaz RAG, Valentin DV, Almeda-Valdes P. Effects of the non-nutritive sweeteners on glucose metabolism and appetite regulating hormones: Systematic review of observational prospective studies and clinical Trials. PLoS One. 2016;11(8):1–17.
  10. Folz J, Culver RN, Morales JM, Grembi J, Triadafilopoulos G, Relman DA, et al. Human metabolome variation along the upper intestinal tract. Nat Metab. 2023 May 10;5(5):777–88.
  11. Shalon D, Culver RN, Grembi JA, Folz J, Treit P V., Shi H, et al. Profiling the human intestinal environment under physiological conditions. Nature. 2023 May 18;617(7961):581–91.
  12. Tey SL, Salleh NB, Henry CJ, Forde CG. Effects of non-nutritive (artificial vs natural) sweeteners on 24-h glucose profiles. Eur J Clin Nutr. 2017 Sep 5;71(9):1129–32.
  13. Renwick AG, Molinary S V. Sweet-taste receptors, low-energy sweeteners, glucose absorption and insulin release. British Journal of Nutrition. 2010;104(10):1415–20.
  14. WHO Nutrition and Food Safety Team. Health effects of the use of non-sugar sweeteners: a systematic review and meta-analysis. Geneva; 2022 Apr.